Abstract
Photoacoustic tomographic imaging is a non-invasive medical diagnostic technology for visualizing biological tissue. However, the inverse problem and noise in photoacoustic signals often cause blurred images. Existing regularization methods struggle with staircasing artifacts and edge preservation. To overcome this, an objective function incorporating total generalized variation (TGV) is proposed. However, it failed with high-density Gaussian noise. To address this, an extended version called edge-guided second-order TGV (ESTGV) is introduced. For sparsification, wavelet transform and discrete cosine transform are introduced, while the fast-composite-splitting algorithm is employed for the inverse problem solution. Experimental validation demonstrates the potential of these approaches.
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Data availability
The DRIVE dataset is available in [42].
42. J. J. Staal, M. D. Abramoff, M. Niemeijer, M. A. Viergeyer, and B. V. Ginneken, “Ridge-based vessel segmentation in color images of the retina,” IEEE Trans. Med. Imaging 23, 501–509 (2004). [CrossRef]
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