Abstract
Near-infrared Raman spectroscopy with a 782-nm cw laser was used to examine lymph node biopsy specimens from women with ruptured breast implants containing silicone gel. For reduction of fluorescence and sample radiation damage, a low-power (30 mW) Ti: sapphire laser, single-stage spectrograph, and CCD detector were employed. Silicone Raman features were clearly visible in lymph node tissue of patients with leaking implants, and the spectra were easily distinguished from those of normal lymph node tissue. The technique has promise for medical diagnostic purposes, and may be amenable to <i>in vivo</i> analysis with adaptation to a fiber-optic probe.
PDF Article
More Like This
Raman spectroscopy: a real-time tool for identifying microcalcifications during stereotactic breast core needle biopsies
A. Saha, I. Barman, N. C. Dingari, S. McGee, Z. Volynskaya, L. H. Galindo, W. Liu, D. Plecha, N. Klein, R. R. Dasari, and M. Fitzmaurice
Biomed. Opt. Express 2(10) 2792-2803 (2011)
Cited By
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Login to access Optica Member Subscription