Abstract
We propose the optimizing design of illumination pattern in partially coherent optical diffraction tomography (PC-ODT), and the custom-build quantitative criterion is demonstrated to maximize the performance of POTF related to the “goodness” evaluation of an illumination aperture. Source modulation with different segment scale and gray scale is implemented to acquire arbitrary distribution source, and the corresponding three-dimensional (3D) phase optical transfer function (POTF) can be easy obtained through the numerical incoherent superstition of each segment components. Further, the simulation and experimental results is presented support this finding as well, and the proposed method is expected to find versatile applications in biological and biomedical research.
© 2021 The Author(s)
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